SEOM guidelines for the management of Malignant Melanoma 2015.
نویسندگان
چکیده
All melanoma patients must be confirmed histologically and resected according to Breslow. Sentinel node biopsy must be done when tumor is over 1 mm or if less with high-risk factors. Adjuvant therapy with interferon must be offered for patients with high-risk melanoma and in selected cases radiotherapy can be added. Metastatic melanoma treatment is guided by mutational BRAF status. BRAF wild type patients must receive anti-PD1 therapy and BRAF mutated patients BRAF/MEK inhibitors or anti-PD1 therapy. Up to 10 years follow up is recommended for melanoma patients with dermatologic examinations and physical exams.
منابع مشابه
Diagnosis and Management of a Malignant Dermal Melanoma in a Donkey (Equus asinus)
Case Description- A 2-yr-old intact male donkey (Equus asinus) was presented to Hospital of Veterinary Medicine, Mansoura University with subcutaneous masses under the tail. Clinical Findings- Physical examination revealed the presence of 2 separate 5x10 and 5x8-cm-diameter, round and firm subcutaneous masses. Treatment and Outcome<...
متن کاملThe Value of Technetium-99m Labeled Alpha-Melanocyte- Stimulating Hormone (99mTc-α-MSH) in Diagnosis of Primary and Metastatic Lesions of Malignant Melanoma
Objective(s): Malignant melanoma is the most lethal type of skin cancers with unfavorable prognosis. Alpha-MSH peptide analogues have a high affinity for melanocortine-1 (MC1) receptors on melanocytes overexpressing in malignant melanoma cells. Pre-clinical studies have shown promising results for radiolabeled MSH imaging in this malignancy. The purpose of this study is to assess the diagnostic...
متن کاملSEOM clinical guidelines in early-stage breast cancer 2015
Breast cancer is a major public health problem. Despite remarkable advances in early diagnosis and treatment, one in three women may have metastases since diagnosis. Better understanding of prognostic and predictive factors allows us to select the most appropriate adjuvant therapy in each patient. In these guidelines, we summarize current evidence for the medical management of early-stage breas...
متن کاملPrimary Malignant Melanoma of the Eye in a 17-Year-Old Girl with Acute Lymphoblastic Leukemia
Herein we describe a case of intraocular melanoma in a17-year old leukemic patient. The history, histological findings of the enucleated eye, blood and bone marrow of the patient were investigated. The enucleated eye contained epitheloid cell type melanoma instead of leukemic cell infiltration. We conclude that intraocular malignant melanoma can occur in acute lymphoblastic leukemia.
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico
دوره 17 12 شماره
صفحات -
تاریخ انتشار 2015